Which system is primarily responsible for protection and support in the human body?

The integumentary system is primarily responsible for protection and support in the human body. This system includes the skin, hair, nails, and various glands, serving as the body's first line of defense against environmental hazards such as pathogens, UV radiation, and physical injuries. The skin acts as a barrier, preventing harmful substances from entering the body and helping to maintain homeostasis by regulating temperature and moisture. Additionally, the integumentary system provides structural support through its layers, contributing to the overall integrity of the body.

In contrast, while the skeletal system does provide structural support and protection for vital organs, it is not referred to as the primary system responsible for protection in a broad sense. The muscular system primarily facilitates movement rather than direct protection. The nervous system is critical for communication and control within the body but does not provide physical protection or support. Hence, the integumentary system's multifaceted role in safeguarding the body underscores its significance in the realm of protection and support.